The Callisto Protocol will come out of the Alien Isolation horror book and use intelligent mutant monsters to cause unscript horror.

Speaking to TechRadar Gaming at Gamescom 2022, Technical Director Mark James says the Callisto protocol will contain a “variable environment” that will change regardless of the player. He describes the game as a “simulated world” that will keep running but will be gradually changed by the behavior of enemies.

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